基于聚焦性能对经颅磁线圈的影响，针对聚焦型线圈商用不足的问题，设计一种具有高聚焦性的单通道双梯形双层线圈。首先使用球头模型分析不同尺寸、相同结构的线圈性能，得到较优的线圈尺寸;为进一步提升聚焦度，再以中尺寸线圈为研究目标，探讨五种不同结构的双层线圈与两种商用8字形线圈的性能差异，得到最优线圈的结构;最后使用50组存在个体差异性的真实脑模型进行仿真验证，分析球头模型结果的可靠性。仿真结果表明:使用球头模型时，优化后的新型线圈对比70 mm figure-8 coil的聚焦度提升了69。48％，刺激深度减少了27。18％;对比25 mm figure-8 coil的聚焦度提升了44。78％，刺激深度减少了8。5％;使用50组真实脑模型时，优化后的新型线圈对比70 mm figure-8 coil的聚焦度提升了62。07％，刺激深度减少了25。71％;对比25 mm figure-8 coil的聚焦度提升了39。49％，刺激深度减少了9。5％。两种模型仿真数据结果趋于一致，证实了仿真可靠性的同时也证明了新型线圈具有更强的刺激强度和聚焦度，能大大提升TMS治疗的安全性，减少不适感，同时单通道设计易于实现，具有较高的性能优势。
Design of Double-trapezoidal and Double-layer Transcranial Magnetic Coil with High Focality
Based on the influence of focality on transcranial magnetic coil,a single-channel double-trapezoidal and double-layer coil with high focality was designed to address the insufficient commercial use. Firstly,the ball-head model was used to analyze the coils with same structure but different sizes,and the better coil size was obtained. In order to further improve the focality,the differences of medium-size coil between five different structures of double-layer coils and two commercial figure-8 coils were analyzed,and the optimal coil structure was obtained. Finally,50 groups of real brain models with individual differences were used for simulation verification. The simulation results indicated that when using the ball-head model,the optimized coil improved the focality by 69.48％ and reduced the depth by 27.18％ compared with the 70 mm figure-8 coil,the focality was improved by 44.78％,and the depth was reduced by 8.5％ compared with 25 mm figure-8 coil. When using 50 groups of real brain models,the focality of the optimized coil was improved by 62.07％ and the depth was reduced by 25.71％ compared with the 70 mm figure-8 coil,the focality was improved by 39.49％,and the depth was reduced by 9.5％ compared with 25 mm figure-8 coil. Experiment results of two models tended to be consistent,which confirmed the reliability of the simulation and also proved that the optimized coil had stronger stimulation intensity and focality,which could greatly improve the safety of TMS treatment and reduce discomfort. At the same time,the single-channel design was easy to implement and had high performance.
electromagnetic inductionfocalitytranscranial magnetic stimulationSim4Lifebrain model
万方数据
维普
