Determination of antibody dynamics of combined oil-emulsion inactivated vaccine of newcastle disease-infectious bronchitis-egg drop syndrome
The 120-day-old laying hens were divided into eight groups and injected with different immune doses of combined oil emulsion inactivated vaccine of newcastle disease,infectious bronchitis and egg drop syndrome,and the eighth group was set up as a blank group.Blood samples were collected and serum was collected for antibody detection on different days after immunization.The results showed that all immune doses could produce antibodies,but the antibody produced by 0.02 mL was slow,disappeared quickly,had a low peak and a short time.There was no significant difference in antibody levels between 0.3,0.4,0.5 and 0.6 mL.A 1 mL immune dose produces antibodies that are fast and long-lasting,with a long peak time.The results showed that the antibody production and level were proportional to the immune dose in a certain immune dose range.
Newcastle diseaseinfectious bronchitis of chickenegg drop syndromeoil-emulsion inactivated vaccineantibody dynamics