首页|Diagnosis and management of malaria in the intensive care unit
Diagnosis and management of malaria in the intensive care unit
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Malaria is responsible for approximately three-quarters of a million deaths in humans globally each year.Most of the morbidity and mortality reported are from Sub-Saharan Africa and Asia,where the dísease is endemic.In non-endemic areas,malaria is the most common cause of imported infection and is associated with significant mortality despite recent advancements and investments in elimination programs.Severe malaria often requires in-tensive care unit admission and can be complicated by cerebral malaria,respiratory distress,acute kidney injury,bleeding complications,and co-infection.Intensive care management includes prompt diagnosis and early initi-ation of effective antimalarial therapy,recognition of complications,and appropriate supportive care.However,the lack of diagnostic capacities due to limited advances in equipment,personnel,and infrastructure presents a challenge to the effective diagnosis and management of malaria.This article reviews the clinical classification,diagnosis,and management of malaria as relevant to critical care clinicians,highlighting the role of diagnostic capacity,treatment options,and supportive care.
MalariaIntensive care unitSevere malariaAntimicrobial resistanceAntimalarialsArtemisinin-based combination therapy
George Akafity、Nicholas Kumi、Joyce Ashong
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Department of Research,Monitoring,and Evaluation,Cape Coast Teaching Hospital,Cape Coast,Ghana
Intensive Care Unit,Department of Critical Care and Anesthesia,Cape Coast Teaching Hospital,Cape Coast,Ghana
Department of Paediatrics and Child Health,Cape Coast Teaching Hospital,Cape Coast,Ghana