首页|Intensive care unit-acquired weakness:Recent insights
Intensive care unit-acquired weakness:Recent insights
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Intensive care unit-acquired weakness(ICU-AW)is a common complication in critically ill patients and is associ-ated with a variety of adverse outcomes.These include the need for prolonged mechanical ventilation and ICU stay;higher ICU,in-hospital,and 1-year mortality;and increased in-hospital costs.ICU-AW is associated with multiple risk factors including age,underlying disease,severity of illness,organ failure,sepsis,immobilization,receipt of mechanical ventilation,and other factors related to critical care.The pathological mechanism of ICU-AW remains unclear and may be considerably varied.This review aimed to evaluate recent insights into ICU-AW from several aspects including risk factors,pathophysiology,diagnosis,and treatment strategies;this provides new perspectives for future research.
Intensive care unit-acquired weaknessMuscle weaknessMuscle atrophyRisk factorMechanismTreatment
Juan Chen、Man Huang
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Department of General Intensive Care Unit,The Second Affiliated Hospital of Zhejiang University School of Medicine,Hangzhou 310009,Zhejiang,China