首页|Comparative study on the incidence of non-COVID-19 viral pneumonia before and after the COVID-19 pandemic:A retrospective analysis based on respiratory non-COVID viral nucleic acid results

Comparative study on the incidence of non-COVID-19 viral pneumonia before and after the COVID-19 pandemic:A retrospective analysis based on respiratory non-COVID viral nucleic acid results

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Background:The impact of the coronavirus disease 2019(COVID-19)pandemic on the etiology of non-COVID-19 viral pneumonia remains to be identified.We investigated the evolution of non-COVID-19 viral pneumonia in hospitalized patients before and after the COVID-19 pandemic.Methods:This is a single-center retrospective study.Patients who came to West China Hospital of Sichuan Univer-sity diagnosed with non-COVID-19 viral pneumonia from January 1,2016 to December 31,2021,were included and divided into pre-and post-COVID-19 groups according to the date of the COVID-19 outbreak in China.The results of 13 viral nucleic acid tests were compared between the two groups.Results:A total of 5937 patients(3954 in the pre-COVID-19 group and 1983 in the post-COVID-19 group)were analyzed.Compared with the pre-COVID-19 group,the proportion of patients tested for respiratory non-COVID-19 viral nucleic acid was significantly increased in the post-COVID-19 group(14.78%vs.22.79%,P<0.05).However,the non-COVID-19 virus-positive rates decreased from 37.9%to 14.6%after the COVID-19 outbreak(P<0.001).Notably,non-COVID-19 viral pneumonia caused by the influenza A virus H1N1(InfAH1N1)(2009)dropped to 0%after the pandemic.The top three viruses were InfAH1N1(2009)(13.9%),human rhinovirus(7.4%),and human adenovirus(3.4%)in the pre-COVID-19 group,and human rhinovirus(3.8%),human respiratory syncytial virus(2.0%),human parainfluenza virus(1.1%)and InfAH3N2(1.1%)in the post-COVID-19 group.Conclusions:The proportion of non-COVID-19 viral pneumonia decreased significantly after the COVID-19 out-break,among which InfAH1N1(2009)pneumonia decreased the most dramatically.

COVID-19Virus nucleic acidInfluenza virus,H1N1

Xiaojiao Tan、Zheng Zhang、Huan Zhang、Jianbo Li、Xuewei Yang、Lijie Wang、Xuelian Liao

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Department of Critical Care Medicine,West China Hospital,Sichuan University,Chengdu,Sichuan,China

Department of Critical Care Medicine,West China Tianfu Hospital,Sichuan University,Chengdu,Sichuan,China

National Key Research and Development ProgramSichuan Science and Technology Program

2022YFC20098042021YFS0003

2024

重症医学(英文)

重症医学(英文)

ISSN:
年,卷(期):2024.4(4)