Bronsted acid-promoted three-component reaction of 2-methoxythiophene, sulfinates and water: Synthesis of gamma-mercapto-beta-sulfonyl esters
Chen, Xianlie 1Luo, Yixin 1Zeng, Qingle1
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作者信息
1. Chengdu Univ Technol
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Abstract
A facile Bronsted acid-promoted three-component reaction of 2-methoxythiophene, sulfinates and water at room temperature has been discovered. Under the mild conditions, a series of gamma-mercapto-beta-sulfonyl esters were obtained in moderate to good yields. The control experiments support the reaction mechanism involves in three processes: 1,5-H shift, Michael addition and ring opening in water. (C) 2022 Elsevier Ltd. All rights reserved.
NSTL
Elsevier