首页|Bioactive Composites based on Calcium Phosphates for Bone Regeneration
Bioactive Composites based on Calcium Phosphates for Bone Regeneration
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Trans Tech Publications Ltd
Development of second generation-bioactive ceramics has been a major progress in the biomaterials field. Although the use of these ceramics is limited to certain applications due to mechanical restrictions, at present they are widely used as bone substitutes in orthopedics and traumatology. Composite materials offer the possibility to combine the advantages of bioactive ceramics and polymers matrices in order to develop materials with tailored chemical and mechanical properties able to regenerate the bone tissue.Either bone fixation or regeneration applications require smart osteoconductive, osteoinductive and osteogenic biomaterials able to deliver signals that, as a consequence, will guide cell behavior and will trigger new tissue repair and regeneration processes. In this context, bioactive ceramics, glass-ceramics and glasses play a key role. Their use and intelligent combination with specific polymers and biomolecules using different elaboration techniques will allow the availability of a variety of composite materials with a wide spectrum of physico-chemical properties, structures and scales for the regeneration of bone tissue.
Melba Navarro、Josep A. Planell
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Institute for Bioengineering of Catalonia (IBEC), CIBER-BBN, C/Baldiri Reixac 10-12, Barcelona 08028, Spain