首页|Calcium phosphate ceramics as bone drug-combined devices

Calcium phosphate ceramics as bone drug-combined devices

扫码查看
The integration of drugs and devices is a growing force in the medical industry. The incorporation of pharmaceutical products not only promises to expand the therapeutic scope of device technology but to access combination products whose therapeutic value stem equally from both the structural attributes of the device and the intrinsic therapy of the drug. For example, the orthopedic industry is exploring drug-coated hip, knee and bone reconstruction implants capable of promoting healing as an added therapeutic benefit for device recipients. In this context, the drug is eluted locally, being targeted in a specific site of interest, thus offering a convenient strategy to avoid adverse effects commonly observed for systemic treatments of some diseases, as an additional benefit. In addition, these new technologies are generally well adapted to the development of minimally invasive surgery for their implantation. Much research is currently being conducted in the area of bone drug delivery system because of the interest for bone tissue engineering.

calcium phosphate ceramicsdrug-combined devicesapatitesbone

Elise Verron、Jean-Michel Bouler

展开 >

Nantes Atlantique Universites, INSERM UMR 791, LIOAD, BP 84215, 44042 Nantes, France

2010

Key engineering materials

Key engineering materials

ISSN:1013-9826
年,卷(期):2010.441
  • 2
  • 105