Infiltrative brain tumors often seamlessly invade healthy brain tissue, posing a challenge for neurosur-geons trying to determine the tumors' boundaries. Livia Eberlin et al. (pp. 1611-1616) developed a mass spec-trometry-based strategy to rapidly characterize brain tumors based on their lipid profiles. The authors first acquired lipid profiles from 21 glioma and 11 meningioma samples using a technique called desorption electro-spray ionization mass spectrometry (DESI-MS), and used the mass spectra to develop a classification system to distinguish between these two primary types of brain tumors.
2013
Proceedings of the National Academy of Sciences of the United States of America