首页|Integrated Closed-loop Control of Bio-actuation for Proprioceptive Bio-hybrid Robots
Integrated Closed-loop Control of Bio-actuation for Proprioceptive Bio-hybrid Robots
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NETL
NSTL
According to news reporting based on a preprint abstract, our journalists obtained the following quote sourced from biorxiv.org: "Biohybrid robots are emergent soft robots that combine engineered artificial structures and living biosystems to exploit unique characteristics of biological cells and tissues. Skeletal muscle tissue-based bio-actuators can respond to externally applied stimuli, such as electrical fields. "However, current bio-actuation systems rely on open-loop control strategies that lack knowledge of the actuator state. The regulation of output force and position of bio-hybrid robots requires self-sensing control systems that combine bio-actuators with sensors and control paradigms. Here, we propose a soft, fibershaped mechanical sensor based on a composite with piezoresistive properties that efficiently integrates with engineered skeletal muscle tissue and senses its contracting states in a cell culture environment in the presence of applied electrical fields. After testing the sensor insulation and biocompatibility, we characterized its sensitivity for typical strains (＜1%) and proved its ability to detect motions from contractile skeletal muscle tissue constructs. Finally, we showed that the sensor response can feed an autonomous control system, thus demonstrating the first proprioceptive bio-hybrid robot that can sense and respond to its contraction state.
NETL
NSTL
