首页|University of Naples Federico Ⅱ Reports Findings in Diabetes Insipidus (Prediction of diabetes insipidus occurrence after endoscopic endonasal removal of sellar lesions using MRI-based radiomics and machine learning)
University of Naples Federico Ⅱ Reports Findings in Diabetes Insipidus (Prediction of diabetes insipidus occurrence after endoscopic endonasal removal of sellar lesions using MRI-based radiomics and machine learning)
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New research on Nutritional and Metabolic Diseases and Conditions - Diabetes Insipidus is the subject of a report. According to news reporting from Naples, Italy, by NewsRx journalists, research stated, “Pituitary adenomas and craniopharyngiomas are the most common lesions of the sellar region. These tumors are responsible for invasion or compression of crucial neurovascular structures.” The news correspondents obtained a quote from the research from the University of Naples Federico II, “The involvement of the pituitary stalk warrants high rates of both pre- and post- operative diabetes insipidus. The aim of our study was to assess the accuracy of machine learning analysis from preoperative MRI of pituitary adenomas and craniopharyngiomas for the prediction of DI occurrence. All patients underwent MRI exams either on a 1.5- or 3-T MR scanner from two Institutions, including coronal T2- weighted (T2-w) and contrast-enhanced T1-weighted (CE T1-w) Turbo Spin Echo sequences. Feature selection was carried out as a multi-step process, with a threshold of 0.75 to identify robust features. Further feature selection steps included filtering based on feature variance (threshold >0.01) and pairwise correlation (threshold <0.80). A Bayesian Network model was trained with 10-fold cross validation employing SMOTE to balance classes exclusively within the training folds. Thirty patients were included in this study. In total 2394 features were extracted and 1791 (75%) resulted stable after ICC analysis. The number of variant features was 1351 and of non-colinear features was 125. Finally, 10 features were selected by oneR ranking. The Bayesian Network model showed an accuracy of 63% with a precision of 77% for DI prediction (0.68 area under the precision-recall curve).”
NaplesItalyEuropeAdenomasBayesian NetworksCraniopharyngiomasCyborgsDiabetes InsipidusEmerging TechnologiesEndocrine System Diseases and ConditionsHealth and MedicineMachine LearningNutritional and Metabolic Diseases and ConditionsOncologyPituitary AdenomaPituitary Diseases and Conditions