首页|Patent Application Titled "Coaxial Needle Adapter And Guide Bracket For Robotic Liquid Handling Platform" Published Online (USPTO 20240082110)
Patent Application Titled "Coaxial Needle Adapter And Guide Bracket For Robotic Liquid Handling Platform" Published Online (USPTO 20240082110)
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By a News Reporter-Staff News Editor at Robotics & Machine Learning Daily News Daily News-According to news reporting originatin g from Washington, D.C., by NewsRx journalists, a patent application by the inve ntors Johnson, Michael A. (Thousand Oaks, CA, US); Umstead, Russell Blake (Thous and Oaks, CA, US), filed on February 1, 2022, was made available online on March 14, 2024. No assignee for this patent application has been made. Reporters obtained the following quote from the background information supplied by the inventors: "Drugs are administered to treat a variety of conditions and d iseases. These drug dosings may be performed in a healthcare facility, or in som e instances, at remote locations such as a patient's home. In certain applicatio ns, a drug product may be shipped to a healthcare facility (e.g., an inpatient f acility, an outpatient facility, and/or a pharmacy) in a powdered or lyophilized form or alternatively in a liquid form. "When reconstituting these drugs for administration, it is desirable to maintain a clean and/or sterile environment so as to not taint or otherwise damage the q uality of the drug or otherwise impact development. Additionally, some classes o f drugs such as bi-specific T-cell engagers may require exceptionally accurate q uantities of the drug product and/or other fluids required for dosing. Oftentime s, the healthcare professional must prepare the drug by closely following a set of steps to ensure a sterile environment is maintained and that correct quantiti es of ingredients are added to the delivery container. As a result, the reconsti tution process may be time-consuming, tedious, and may have an unacceptable or u ndesirable error rate. Development of robotic based analytical workflows for lyo philized drug products has resulted in a reduction of time and labor intensive s ample preparation tasks in addition to the mitigation of safety concerns such as exposure to needles during drug reconstitution. These new workflows may reconst itute lyophilized samples autonomously or semi-autonomously, extract the samples from sealed containers, and/or perform sample preparation steps such as dispens ing samples into a microwell plate for measuring protein concentrations, each wi th minimal or no manual intervention.
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