首页|Aarhus University Reports Findings in Robotics (An RNA origami robot that traps and releases a fluorescent aptamer)
Aarhus University Reports Findings in Robotics (An RNA origami robot that traps and releases a fluorescent aptamer)
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By a News Reporter-Staff News Editor at Robotics & Machine Learning Daily News Daily News-New research on Robotics is the subjec t of a report. According to news reporting out of Aarhus, Denmark, by NewsRx edi tors, research stated, "RNA nanotechnology aims to use RNA as a programmable mat erial to create self-assembling nanodevices for application in medicine and synt hetic biology. The main challenge is to develop advanced RNA robotic devices tha t both sense, compute, and actuate to obtain enhanced control over molecular pro cesses." Our news journalists obtained a quote from the research from Aarhus University, "Here, we use the RNA origami method to prototype an RNA robotic device, named t he ‘Traptamer,' that mechanically traps the fluorescent aptamer, iSpinach. The T raptamer is shown to sense two RNA key strands, acts as a Boolean AND gate, and reversibly controls the fluorescence of the iSpinach aptamer. Cryo-electron micr oscopy of the closed Traptamer structure at 5.45-angstrom resolution reveals the mechanical mode of distortion of the iSpinach motif." According to the news editors, the research concluded: "Our study suggests a gen eral approach to distorting RNA motifs and a path forward to build sophisticated RNA machines that through sensing, computing, and actuation modules can be used to precisely control RNA functionalities in cellular systems." For more information on this research see: An RNA origami robot that traps and r eleases a fluorescent aptamer. Science Advances, 2024;10(12). Science Advances can be contacted at: Amer Assoc Advancement Science, 1200 New York Ave, NW, Was hington, DC 20005, USA.
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