Abstract
By a News Reporter-Staff News Editor at Robotics & Machine Learning Daily News Daily News-New research on Biomedical Engineering - Tissue Engineering is the subject of a report.According to news reporting ou t of Timisoara,Romania,by NewsRx editors,research stated,"Biomaterials are e ssential in modern medicine,both for patients and research.Their ability to ac quire and maintain functional vascularization is currently debated." Our news journalists obtained a quote from the research,"The aim of this study was to evaluate the vascularization induced by two collagen-based scaffolds (wit h 2D and 3D structures) and one non-collagen scaffold implanted on the chick emb ryo chorioallantoic membrane (CAM).Classical stereomicroscopic image vascular a ssessment was enhanced with the IKOSA software by using two applications:the CA M assay and the Network Formation Assay,evaluating the vessel branching potenti al,vascular area,as well as tube length and thickness.Both collagen-based sca ffolds induced non-inflammatory angiogenesis,but the non-collagen scaffold indu ced a massive inflammation followed by inflammatory-related angiogenesis.Vessel s branching points/Region of Interest (Px.2) and Vessel branching points/Vessel total area (Px.2),increased exponentially until day 5 of the experiment certify ing a sustained and continuous angiogenic process induced by 3D collagen scaffol ds.Collagen-based scaffolds may be more suitable for neovascularization compare d to non-collagen scaffolds.The present study demonstrates the potential of the CAM model in combination with AI-based software for the evaluation of vasculari zation in biomaterials."
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