摘要
由一名新闻记者-机器人与机器学习每日新闻的工作人员新闻编辑-来自华盛顿特区,NewsRx记者报道,发明者ABBOTT,Charles Wilber(加利福尼亚州圣莱安德罗);BOYLE,Sean Michael(加利福尼亚州圣莱安德罗);CHEN,Richard(加利福尼亚州门洛帕克);DEA,Steven(加利福尼亚州山景城,美国);LEVY,美国);W EST,John(Cupertino,CA,US);ZHANG,Simo V.(Union City,CA,US),2022年4月21日提交,2024年6月6日在线提供。本专利申请没有受让人。新闻编辑从发明人提供的背景信息中获得了以下引文:“免疫检查点通常指一组硬连接到免疫系统中的抑制途径,其调节生理免疫应答的持续时间和幅度。”pd-1(PD-1)抑制免疫系统,以防止其不分青红皂白地粘附细胞,虽然免疫检查点通常是有效的,但肿瘤细胞可能操纵这种机制,阻止免疫系统清除肿瘤细胞。
Abstract
By a News Reporter-Staff News Editor at Robotics & Machine Learning Daily News-From Washington, D.C., NewsRx journalists report that a patent application by the inventors ABBOTT, Charles Wilbur (San Leandro, CA, US); BOYLE, Sean Michael (San Leandro, CA, US); CHEN, Richard (Menlo Park, C A, US); DEA, Steven (Mountain View, CA, US); LEVY, Eric (Newark, CA, US); MELLAC HERUVU, Dattatreya (Union City, CA, US); PYKE, Rachel Marty (Oakland, CA, US); W EST, John (Cupertino, CA, US); ZHANG, Simo V. (Union City, CA, US), filed on Apr il 21, 2022, was made available online on June 6, 2024. No assignee for this patent application has been made. News editors obtained the following quote from the background information suppli ed by the inventors: "Immune checkpoints generally refer to a set of inhibitory pathways hardwired into the immune system, which regulate the duration and ampli tude of physiological immune responses. When activated, the immune checkpoint mo lecules (e.g., PD-1) suppresses the immune system in order to prevent it from at tacking cells indiscriminately. Although immune checkpoints are generally effect ive, tumor cells may manipulate such mechanism to prevent the immune system from eliminating tumor cells.