首页|Sichuan University of Science and Engineering Reports Findings in Stroke (Altere d Intrinsic Brain Activity in Ischemic Stroke Patients Assessed Using the Percen t Amplitude of a Fluctuation Method)
Sichuan University of Science and Engineering Reports Findings in Stroke (Altere d Intrinsic Brain Activity in Ischemic Stroke Patients Assessed Using the Percen t Amplitude of a Fluctuation Method)
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By a News Reporter-Staff News Editor at Robotics & Machine Learning Daily News Daily News – New research on Cerebrovascular Diseas es and Conditions - Stroke is the subject of a report. According to news reporti ng out of Zigong, People’s Republic of China, by NewsRx editors, research stated , “Ischemic stroke is a vascular disease that may cause cognitive and behavioral abnormalities. This study aims to assess abnormal brain function in ischemic st roke patients using the percent amplitude of fluctuation (PerAF) method and furt her explore the feasibility of PerAF as an imaging biomarker for investigating i schemic stroke pathophysiology mechanisms.” Our news journalists obtained a quote from the research from the Sichuan Univers ity of Science and Engineering, “Sixteen ischemic stroke patients and 22 healthy controls (HCs) underwent resting state functional magnetic resonance imaging (r s-fMRI) scanning, and the resulting data were analyzed using PerAF. Then a corre lation analysis was conducted between PerAF values and Mini-Mental State Examina tion (MMSE) and Montreal Cognitive Assessment (MoCA) scores. Finally, the abnorm al PerAF values were extracted and defined as features for support vector machin e (SVM) analysis. Compared with HCs, ischemic stroke patients showed decreased P erAF in the bilateral cuneus, left middle frontal gyrus, precuneus and right inf erior temporal gyrus, and increased PerAF in the bilateral orbital part of middl e frontal gyrus and right orbital part of superior frontal gyrus. Correlation an alyses revealed that PerAF values in the left orbital part of middle frontal gyr us was negatively correlated with the MoCA scores. The SVM classification of the PerAF values achieved an area under the curve (AUC) of 0.98 and an accuracy of 94.74%. Abnormal brain function has been found among ischemic strok e patients, which may be correlated with visual impairment, attention deficits, and dysregulation of negative emotions following a stroke.”
ZigongPeople’s Republic of ChinaAsiaBiomarkersCerebrovascular Diseases and ConditionsDiagnostics and ScreeningHealth and MedicineStroke
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