首页|Royal Surrey County Hospital Reports Findings in Prostatectomy (Predictors of bi ochemical recurrence after robot-assisted radical prostatectomy: single-centre a nalysis)
Royal Surrey County Hospital Reports Findings in Prostatectomy (Predictors of bi ochemical recurrence after robot-assisted radical prostatectomy: single-centre a nalysis)
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By a News Reporter-Staff News Editor at Robotics & Machine Learning Daily News Daily News – New research on Surgery - Prostatectom y is the subject of a report. According to news reporting originating in Surrey, United Kingdom, by NewsRx journalists, research stated, “We evaluated risk fact ors for biochemical recurrence (BCR) after robot-assisted radical prostatectomy (RARP) based on our department database. Patients who underwent RARP between 201 8 and 2020 were identified and included in our retrospective study.” The news reporters obtained a quote from the research from Royal Surrey County H ospital, “Patients who received neoadjuvant treatment, patients with positive ly mph nodes, salvage prostatectomies, and patients with missing data were excluded . BCR was defined as PSA 0.2 ng/ml. Parameters that were investigated were the I nternational Society of Urological Pathologists (ISUP) score, stage, and positiv e surgical margins (PSM) as they were reported in the pathology report. A subgro up analysis based on the tumour stage was performed. A total of 414 patients wer e included in the analysis. Seventy-seven of them experienced BCR. Based on mult ivariable analysis, ISUP grade was a strong predictor for BCR with odds ratio (O R): 2.86 (CI: 1.49-5.65; p = 0.002), OR: 5.90 (CI: 1.81-18.6; p = 0.003), OR: 4. 63 (CI: 1.79-11.9; p = 0.001) for ISUP grade 3, 4, 5, respectively. Regarding tu mour stage, pT2 and pT3a did not show any significant difference in predicting B CR (p = 0.11), whereas pT3b stage was a predictor for BCR with OR: 6.2 (CI: 2.25 -17.7; p<0.001). In the subgroup analysis for 206 patients with pT2 disease, ISUP group and PSM were predictors for BCR. On the other hand , when patients with pT3 disease were inspected, the only parameter that was pre dictive of BCR was pT3b disease (OR: 4.68, CI: 1.71-13.6; p = 0.003). ISUP grade , the extent of T3 disease, and the extent and ISUP grade of surgical margins we re not predictors of BCR. The most important risk factors for BCR after RARP are ISUP grade and tumour stage. In pT2 disease, PSM is a significant predictor of BCR, along with high ISUP grade.”
SurreyUnited KingdomEuropeBiochemi calsBiochemistryChemicalsEmerging TechnologiesHealth and MedicineMachi ne LearningMale Urologic Surgical ProceduresMen’s HealthProstatectomyRis k and PreventionRobotRoboticsSurgery
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