首页|Accurate sample deconvolution of pooled snRNA-seq using sexdependent gene expre ssion patterns
Accurate sample deconvolution of pooled snRNA-seq using sexdependent gene expre ssion patterns
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By a News Reporter-Staff News Editor at Robotics & Machine Learning DailyNews Daily News - According to news reporting based on a preprint abstract, our journalists obtained thefollowing quote sourced from bi orxiv.org:“Single nucleus RNA sequencing (snRNA-seq) technology offers unprecedented resol ution for studyingcell type-specific gene expression patterns.“However, snRNA-seq poses high costs and technical limitations, often requiring the pooling of independentbiological samples and loss of individual sample-leve l data. Deconvolution of sample identity usinginherent features would enable th e incorporation of pooled barcoding and sequencing protocols, therebyincreasing data throughput and analytical sample size without requiring increases in exper imental samplesize and sequencing costs.