首页|Traffic-related PM2.5 pollution in Hong Kong: component-specific and source-resolved health risks and cytotoxicity
Traffic-related PM2.5 pollution in Hong Kong: component-specific and source-resolved health risks and cytotoxicity
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NETL
NSTL
Elsevier
Current studies on the source apportionment of fine particulate matter (PM2.5) primarily emphasized the contributions of sources to mass concentrations, leaving the acute and chronic health effects caused by specific sources and components insufficiently addressed. In this study, we integrated source profiles with acute cytotoxicity and chronic health risk to assess the component-specific and source-resolved health effects of PM2.5 in a coastal megacity, Hong Kong. An intracellular reactive oxygen species (ROS) analysis of 24-h integrated PM2.5 samples conducted on the BEAS-2b cell line revealed that trace metals dominantly drove PM2.5-induced ROS (contributing 52 % in roadside, 39 % in general urban, and 32 % for coastal background PM2.5). Among the analyzed metals, the primary culprits were Fe, Zn, and Cu, urging the need for non-exhaust pollution control. This study also provided quantitative evidence for the biological toxic potential of insoluble elemental carbon (EC), constituting 31 % and 22 % of overall ROS induction in roadside and general urban PM2.5, respectively. In conjunction with source profiles, our findings reveal a clear inequality in contributions attributed to the same source when assessed by mass, acute biological toxicity effect, and chronic health risks. For instance, local fresh on-road traffic emissions were predominant in accounting for the acute intracellular ROS induction (84 % in roadside and 63 % in general urban PM2.5). Meanwhile, regional sources brought in by long-rang transport, such as combustion & industrial emissions, posed more threats to chronic inhalation health risks induced by PM2.5, especially for general urban and coastal background aerosols in Hong Kong. This investigation has significant implications for developing toxicity-oriented pollution control strategies.
Traffic-related emissionAcute cytotoxicityChronic health riskTrace metalElemental carbonSOURCE APPORTIONMENTBLACK CARBONAIR-POLLUTIONOXIDATIVE STRESSTOXICITYURBANEMISSIONSCHEMICALSMIXTURESPAHS
The Hong Kong Polytechnic University Department of Civil and Environmental Engineering||Hong Kong Polytech Univ||Southern Univ Sci & Technol
The Hong Kong Polytechnic University Department of Civil and Environmental Engineering||Hong Kong Polytech Univ
The Hong Kong Polytechnic University Department of Civil and Environmental Engineering
The Hong Kong University of Science and Technology School of Science Division of Life Science
The Hong Kong Polytechnic University Department of Civil and Environmental Engineering||Hong Kong Polytech Univ||The Hong Kong Polytechnic University Research Institute for Sustainable Urban Development
NETL
NSTL
Elsevier
