首页|A Catalytic Method for the Synthesis of 3-Cyano-2(l//)-Pyridones Derivatives as Nonsteroidal Cardiotonic Agents Using Nano-Ti02
A Catalytic Method for the Synthesis of 3-Cyano-2(l//)-Pyridones Derivatives as Nonsteroidal Cardiotonic Agents Using Nano-Ti02
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A highly efficient procedure for the synthesis of 3-Cyano-2(lH)-pyridones and their 2-imino isosteres via a one-pot multicomponent reaction of 3,4-dimethoxyacetophenone, malonitrile or ethyl cyanoacetate, an aldehyde, ammonium acetate in the presenceof nano-TiO_2 is achieved in good yields.