Epidemiologists also seek to identify the factors which drive the observed distribution of disease, i.e. those that appear to increase or reduce the probability ("risk") of developing disease. Since aging is associated with increased incidence of AD, it behooves us to explore age-related differences in risk factors for AD across the spectrum from early-onset to "late-late" onset AD. As population-based cohorts are observed over many years, a curious pattern emerging from longitudinal studies might support the following model.
NSTL
Cambridge Univ Press
