首页|Quinolizinium-based tunable pH fluorescent probes for imaging
Quinolizinium-based tunable pH fluorescent probes for imaging
扫码查看
点击上方二维码区域，可以放大扫码查看
原文链接
NSTL
A new class of quinolizinium-based tunable pH fluorescent probes for cell imaging was developed.The probes showed turn"On"fluorescence response upon acidification brought by a modulation of photoinduced electron transfer(PET)from the N,N-dialkyl aniline substituent to the quinolizinium core skeleton.These novel PET-based pH fluorescent probes displayed tunable emission properties in between 478 and 509 nm.Also,the probes exhibited tunable pH responsiveness with pKa ranging from<2.1 to 6.1 contributed by the steric effect of N,N-dialkyl anilines.They were successfully applied to in vivo pH sensing in lysosome in live cells.
pH probeQuinoliziniumPhoto-induced electron transferCellular imaging
Hoi-Yi Sit、Jie-Ren Deng、Wing-Cheung Chan
展开 >
The Hong Kong Polytechnic University Shenzhen Research Institute,Shenzhen,518057,China
State Key Laboratory of Chemical Biology and Drug Discovery,Department of Applied Biology and Chemical Technology,The Hong Kong Polytechnic University,Hung Horn,Hong Kong,China
NSTL
