首页|Experimental study on novel biodegradable Zn–Fe–Si alloys
Experimental study on novel biodegradable Zn–Fe–Si alloys
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NSTL
Wiley
Abstract Bioabsorbable metals are increasingly attracting attention for their potential use as materials for degradable implant devices. Zinc (Zn) alloys have shown great promises due to their good biocompatibility and favorable degradation rate. However, it has been difficult to maintain an appropriate balance among strength, ductility, biocompatibility, and corrosion rate for Zn alloys historically. In this study, the microstructure, chemical composition, mechanical properties, biocompatibility, and corrosion rate of a new ternary zinc?iron–silicon (Zn–Fe–Si) alloy system was studied as a novel material for potential biodegradable implant applications. The results demonstrated that the in situ formed Fe–Si intermetallic phases enhanced the mechanical strength of the material while maintaining a favorable ductility. With Fe–Si reinforcements, the microhardness of the Zn alloys was enhanced by up to 43%. The tensile strength was increased by up to 76% while elongation to failure remained above 30%. Indirect cytotoxicity testing showed the Zn‐Fe‐Si system had good biocompatibility. Immersion testing revealed the corrosion rate of Zn–Fe–Si system was not statistically different from pure Zn. To understand the underlying phase formation mechanism, the reaction process in this ternary system during the processing was also studied via phase evolution and Gibbs free energy analysis. The results suggest the Zn–Fe–Si ternary system is a promising new material for bioabsorbable metallic medical devices.
biocompatibilitybiodegradablein situ formed intermetallicmechanical propertiesZn–Fe–Si alloys
Yuxin Zeng、Zeyi Guan、Chase S. Linsley、Shuaihang Pan、Jingke Liu、Benjamin M. Wu、Xiaochun Li
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Department of Mechanical and Aerospace Engineering,Samueli School of Engineering, University of
Department of Bioengineering,Samueli School of Engineering, University of California
NSTL
Wiley
