首页|Antioxidant and anti-staphylococcal activity of polyphenolic-rich extracts from Ataulfo mango seed
Antioxidant and anti-staphylococcal activity of polyphenolic-rich extracts from Ataulfo mango seed
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NSTL
Elsevier
In recent years, the search for new antioxidant and antimicrobial agents is one of the first subjects of scientific research. The polyphenolic compounds of food byproducts have attracted scientists across the world in the search for new natural substances. In this study, antioxidant (DPPH, ABTS, and TAA) and anti-Staphylococcus aureus (ATCC and clinical isolates strains) activity of mango seed extracts was investigated. The extracts were obtained by Microwave-Assisted Extraction (MAE), Fermentation-Assisted Extraction (FAE), and Solvent-Assisted Extraction (SAE). Chemical profile as well as influence of applied extraction technique were also investigated. The extracts showed potent antioxidant activity with EC50 values (MAE: 27.1 +/- 0.15 mu g/mL, SAE:14.3 +/- 0.37 mu g/ mL and FAE:12.5 +/- 0.41 mu g/mL) higher than Trolox (for DPPH). Higher antibacterial activity was observed (MIC: 7.31-750 mu g/mL and CMB: 156.3-1500 mu g/mL) compared to synthetic antibiotics. Cell wall damage and cell lysis were clearly visualized under Scanning Electron Microscopy (SEM). HPLC-MS allowed the detection of 6 (SAE), 8 (MAE), and 11 (FAE) polyphenolic compounds. These findings suggest that Ataulfo mango seed extracts may be utilized in the developed natural antioxidant and antibacterial agents.
Torres-Leon, Cristian、de Azevedo Ramos, Barbara、dos Santos Correia, T. Maria、Carneiro-da-Cunha, G. Maria、Ramirez-Guzman, Nathiely、Alves, C. Luiz、Brayner, A. Fabio、Ascacio-Valdes, Juan、Alvarez-Perez, B. Olga、Aguilar, N. Cristobal
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Univ Autonoma Coahuila, Sch Chem, Food Res Dept, Saltillo, Coahuila, Mexico
Univ Fed Pernambuco, Ctr Biosci, Dept Biochem, Recife, PE, Brazil
NSTL
Elsevier
