首页|National trends in the surgical management of metastatic lung cancer to the spine using the national inpatient sample database from 2005 to 2014

National trends in the surgical management of metastatic lung cancer to the spine using the national inpatient sample database from 2005 to 2014

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Optimal management of metastatic lung cancer to the spine (MLCS) incorporates a multidisciplinary approach. With improvements in lung cancer screening and nonsurgical treatment, the role for surgery may be affected. The objective of this study is to assess trends in the surgical management of MLCS using the National Inpatient Sample (NIS) database. The NIS was queried for patients with MLCS who underwent surgery from 2005 to 2014. The frequencies of spinal decompression alone, spinal stabilization with or without (+/-) decompression, and vertebral augmentation were calculated. Statistical analysis was performed to analyze the effect of patient characteristics on outcomes. The most common procedure performed was vertebral augmentation (10719, 44.3%), followed by spinal stabilization +/decompression (8634, 35.7%) and then decompression alone (4824, 20.0%). The total number of surgeries remained stable, while the rate of spinal stabilizations increased throughout the study period (p < 0.001). Invasive procedures such as stabilization and decompression were associated with greater costs, length of stay, complications and mortality. Increasing comorbidity was associated with increased odds of complication, especially in patients undergoing more invasive procedures. In patients with low pre-operative comorbidity, the type of procedure did not influence the odds of complication. Graded increases in length of stay, cost and mortality were seen with increasing complication rate. The rate of spinal stabilizations increased, which may be due to either increased early detection of disease facilitating use of outpatient vertebral augmentation procedures and/or the recognition that surgical decompression and stabilization are necessary for optimal outcome in the setting of MLCS with neurological deficit. (c) 2021 Elsevier Ltd. All rights reserved.

Spinal cord tumorComplicationsHospitalization costNationwide inpatient sampleLung cancerSpinal metastasisSpine surgerySURVIVALSURGERYKYPHOPLASTYDISEASE

Zehri, Aqib H.、Peterson, Keyan A.、Lee, Katriel E.、Kittel, Carol A.、Evans, Joni K.、Wilson, Jonathan L.、Hsu, Wesley

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Bowman Gray Sch Med,Wake Forest Univ

2022

Journal of clinical neuroscience

Journal of clinical neuroscience

SCI
ISSN:0967-5868
年,卷(期):2022.95
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