首页|Tridysoxyphenols A and B, two new trimeric sesquiterpene phenols from Dysoxylum parasiticum leaves
Tridysoxyphenols A and B, two new trimeric sesquiterpene phenols from Dysoxylum parasiticum leaves
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NSTL
Elsevier
? 2022 Phytochemical Society of EuropeTwo new sesquiterpene phenol trimers, tridysoxyphenols A (2) and B (3), along with two known compounds, namely a sesquiterpene phenol, (+)-7-hydroxycalamenene (1), and a tetralone derivative, 4-hydroxy-4,7-dimethyl-α-tetralone (4), were isolated from the leaves of Dysoxylum parasiticum (Osbeck) Kosterm. The structures of 2 and 3 were elucidated using nuclear magnetic resonance (NMR) spectroscopy, ultraviolet (UV) spectroscopy, infrared (IR) spectroscopy, high-resolution electrospray ionization time-of-flight mass spectrometry (HR-ESI/TOF-MS), and time-dependent density functional theory (TDDFT) calculations of the electronic circular dichroism (ECD) spectroscopic data. No cytotoxic activity was observed for any of the isolated compounds at low concentrations, although compound 1 suppressed the viability of HL60 cells at 119.85 ± 10.03 μM.
NSTL
Elsevier
