首页|Lower Airway Nitrogen Oxide Levels in Children with Primary Ciliary Dyskinesia Is Linked to Neutrophilic Inflammation
Lower Airway Nitrogen Oxide Levels in Children with Primary Ciliary Dyskinesia Is Linked to Neutrophilic Inflammation
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NSTL
Elsevier
? 2022 Elsevier Inc.Treatment of primary ciliary dyskinesia pulmonary exacerbations resulted in an increase in sputum nitric oxide (NO) metabolites and decrease in neutrophilic inflammation. The association between the 2 suggests that neutrophilic inflammation contributes to airway NO deficiency in primary ciliary dyskinesia and that reducing inflammation may lead to improved airway NO homeostasis. Trial Registry: ClinicalTrials.gov: NCT01155115.
biomarkercystic fibrosislung diseasenitric oxide
Grasemann H.、McDonald N.、Yuan X.Z.、Dell S.、Waters V.、Ratjen F.
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Division of Respiratory Medicine Department of Paediatrics The Hospital for Sick Children
Translational Medicine Research Institute The Hospital for Sick Children
NSTL
Elsevier
