首页|New aspidosperma-type alkaloids from Tabernaemontana bovina

New aspidosperma-type alkaloids from Tabernaemontana bovina

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? 2022 Phytochemical Society of EuropeTwo new aspidosperma-type alkaloids, taberibogines C and D (1 and 2), along with three known ones (3–5), were isolated from the leaves of Tabernaemontana bovina. Their structures including absolute configurations were elucidated by extensive spectroscopic analysis and X-ray crystal diffraction. Alkaloids 1-2 exhibited moderate inhibitory effects on LPS-induced nitric oxide (NO) production in RAW 264.7 macrophages.

AlkaloidsAnti-inflammatory activityAspidosperma-typeTabernaemontana bovina

Zhao X.、Du S.-Y.、Liu J.-N.、Jiang C.-S.、Zhu K.-K.、Fang L.、Liu J.

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School of Biological Science and Technology University of Jinan

Shandong Provincial Engineering Research Center for Medicines of Orthopedic Pain Shandong Mingren Freda Pharmaceutical Co. Ltd

2022

Phytochemistry Letters

Phytochemistry Letters

SCI
ISSN:1874-3900
年,卷(期):2022.49
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