首页|Ibuprofen-loaded calcium phosphate granules: A new bone substitute for local relieving symptoms of osteoarthritis
Ibuprofen-loaded calcium phosphate granules: A new bone substitute for local relieving symptoms of osteoarthritis
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NSTL
Elsevier
Musculoskeletal diseases often demand a drug treatment at the specific site of injury or defect site. In this context, the use of calcium phosphates is attractive as it allows both the bone substitution and the local delivery of a drug substance. In this work, we present a drug delivery device that combines calcium phosphate bioceramic granules and ibuprofen, a widely used anti-inflammatory drug.
Drug delivery systemIbuprofenCalcium phosphate bone substituteIn vitro and in vivo anti-inflammatory effectRheumatoid Arthritis
Limami, Youness、Leger, David Yannick、Liagre, Bertrand、Pecout, Nathalie、Viana, Marylene
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Univ Limoges, Lab PEIRENE, EA 7500, Fac Pharm, 2 Rue Dr Marcland, F-87000 Limoges, France
NSTL
Elsevier
