Tetrahedron letters2022，Vol.964.DOI:10.1016/j.tetlet.2022.153778

Xanalterate A, altertoxin VIII and IX, perylenequinone derivatives from antarctica-sponge-derived fungus Alternaria sp. HDN19-690

Hou, Zhaoxia Sun, Chunxiao Chen, Xuedong Zhang, Guojian Che, Qian Li, Dehai Zhu, Tianjiao
Tetrahedron letters2022，Vol.964.DOI:10.1016/j.tetlet.2022.153778
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  • NSTL
  • Elsevier

Xanalterate A, altertoxin VIII and IX, perylenequinone derivatives from antarctica-sponge-derived fungus Alternaria sp. HDN19-690

Hou, Zhaoxia 1Sun, Chunxiao 1Chen, Xuedong 1Zhang, Guojian 1Che, Qian 1Li, Dehai 1Zhu, Tianjiao1
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作者信息

  • 1. Ocean Univ China
  • 折叠

Abstract

Three new perylenequinone derivatives, namely xanalterate A (1), altertoxin VIII and IX (2 and 3), together with one known analogue, stemphyperylenol (4), were isolated from the extract of the Antarctic sponge-derived fungus Alternaria sp. HDN19-690. The structures of compounds 1-3, including absolute configurations, were confirmed based on the analysis of MS, NMR and ECD data. Compound 1 exhibited promising antimicrobial activity against the tested strains with MIC values ranging from 3.13 to 12.5 mu M. (C) 2022 Elsevier Ltd. All rights reserved.

Key words

Perylenequinone derivatives/Alternaria sp./Antibacterial activity/Secondary metabolites/Marine-derived fungi/BIOSYNTHESIS/SP.

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出版年

2022
Tetrahedron letters

Tetrahedron letters

CCR
ISSN：0040-4039
被引量3
参考文献量25
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