Tetrahedron letters2022，Vol.883.DOI:10.1016/j.tetlet.2021.153555

Microwave mediated synthesis of 2-aminooxazoles

Klug, Trevan Cronin, Adam O'Brien, Eli Schioldager, Ryan Johnson, Hunter Gleason, Cameron Schmid, Connor Soderberg, Nathan Manjunath, Aashrita Liyanage, Duminda Lazaro, Horacio Kimball, Joshua J. Eagon, Scott
Tetrahedron letters2022，Vol.883.DOI:10.1016/j.tetlet.2021.153555
✕
  • NSTL
  • Elsevier

Microwave mediated synthesis of 2-aminooxazoles

Klug, Trevan 1Cronin, Adam 2O'Brien, Eli 1Schioldager, Ryan 3Johnson, Hunter 1Gleason, Cameron 1Schmid, Connor 1Soderberg, Nathan 1Manjunath, Aashrita 1Liyanage, Duminda 4Lazaro, Horacio 5Kimball, Joshua J. 5Eagon, Scott1
扫码查看

作者信息

  • 1. Calif Polytech State Univ San Luis Obispo
  • 2. Univ Calif Berkeley
  • 3. Pfizer La Jolla Campus,10770 Sci Ctr Dr, San Diego, CA 92121 USA
  • 4. Soka Univ Amer
  • 5. Promega Biosci
  • 折叠

Abstract

A microwave mediated synthesis of 2-aminooxazoles at 150 degrees C was developed, providing products with a variety of functional groups. The reaction takes 5 min and provides product with a simple precipitation at moderate to good yields without the need for recrystallization or flash chromatography. (C) 2021 The Author(s). Published by Elsevier Ltd.

Key words

2-Aminooxazole/Microwave/Heterocycles/Isothiocyanate/beta-Keto azide/DERIVATIVES/INHIBITORS

引用本文复制引用

出版年

2022
Tetrahedron letters

Tetrahedron letters

CCR
ISSN：0040-4039
参考文献量14
段落导航相关论文