Abstract
Trifluoromethylpyridine(TFMP) is a biologically active fragment formed by connecting trifluoromethyl and pyridine ring.As a result of its unique physical and chemical properties and outstanding biological activity,a variety of pesticide compounds with the TFMP fragment have been discovered and marketed and have played important roles in crop protection research.It is therefore a timely and valuable task to summarize the rationality on how to create new molecules containing TFMP fragments based on the structure-activity relationships,design mentality,and potential mechanism.This review gives a brief summary on the pesticides containing TFMP fragments in the past 5 years and introduces the latest progress of our group in this field.The aim is to provide readers with a convenient route to touch this topic and hopefully serve some educational purpose for graduate students as well.
NSTL