Tetrahedron letters2022,Vol.1014.DOI:10.1016/j.tetlet.2022.153929

Efficient thiocyanation of aromatic compounds using NH4SCN, DMSO and H2SO4

Abbasi, Mohammad Nowrouzi, Najmeh Sedaghat, Hamed
Tetrahedron letters2022,Vol.1014.DOI:10.1016/j.tetlet.2022.153929

Efficient thiocyanation of aromatic compounds using NH4SCN, DMSO and H2SO4

Abbasi, Mohammad 1Nowrouzi, Najmeh 1Sedaghat, Hamed1
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作者信息

  • 1. Persian Gulf Univ
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Abstract

A simple, efficient, and smooth thiocyanation of indoles, phenols and aniline derivatives using NH4SCN, DMSO and H2SO4 in DMF is introduced. Using this procedure, diverse indoles and N-alkyl indoles are selectively thiocyanated at the C-3 position. para-free anilines, N-alkyl anilines and phenols undergo thiocyanation at the para position selectively. (C) 2022 Elsevier Ltd. All rights reserved.

Key words

Thiocyanation/DMSO/Indole/Phenol/Aniline/PROMOTED ELECTROPHILIC THIOCYANATION/REGIOSELECTIVE THIOCYANATION/HETEROAROMATIC-COMPOUNDS/CATALYTIC THIOCYANATION/AMMONIUM THIOCYANATE/ALPHA-THIOCYANATION/HIGHLY EFFICIENT/INDOLES/PHENOLS/REAGENT

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出版年

2022
Tetrahedron letters

Tetrahedron letters

CCR
ISSN:0040-4039
被引量4
参考文献量55
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