Surface & Coatings Technology2022，Vol.44213.DOI:10.1016/j.surfcoat.2022.128338

Silver oxide coatings deposited on leathers to prevent diabetic foot infections

Carvalho, Isabel Lima, M. Jose Nobre, David Marques, S. Mariana Castro, Debora Leite, Teofilo R. Henriques, Mariana Duarte, Fernando Ramalho, Amilcar Carvalho, Sandra
Surface & Coatings Technology2022，Vol.44213.DOI:10.1016/j.surfcoat.2022.128338
✕
  • NSTL
  • Elsevier

Silver oxide coatings deposited on leathers to prevent diabetic foot infections

Carvalho, Isabel 1Lima, M. Jose 2Nobre, David 2Marques, S. Mariana 2Castro, Debora 2Leite, Teofilo R. 3Henriques, Mariana 2Duarte, Fernando 2Ramalho, Amilcar 1Carvalho, Sandra1
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作者信息

  • 1. Univ Coimbra
  • 2. Univ Minho
  • 3. ICC Ind & Comercio Calcado SA
  • 折叠

Abstract

Diabetic foot is one of the most serious complications of diabetes, the appearance of foot ulcers is highly susceptible to the prevalence of infections. In this sense, thin films of silver (Ag) and silver oxide (AgOx) were deposited by the dc reactive magnetron sputtering technique on different leather substrates for application in insoles and/or footwear inside in order to functionalize them, thus promoting antibacterial properties. A detailed characterization is described to the uncoated and coated leathers. Cytotoxicity and antimicrobial activity were evaluated and, a silver antimicrobial mechanism was suggested. Among the uncoated and coated leathers, AgOx modified samples have higher CoF indicating that this coating can permit higher immobilization of the foot in relation to the skin. The AgOx coating has also impressive antibacterial and antifungal activity without causing any cytotoxic effect, suggesting the potential application of AgOx modified leathers to diabetic specialized footwear.

Key words

AgO x coating/Leather/Sputtering/Antimicrobial mechanism/Cytotoxicity/IN-VITRO/AG/MECHANISMS/MANAGEMENT

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出版年

2022
Surface & Coatings Technology

Surface & Coatings Technology

ISTP
ISSN：0257-8972
参考文献量41
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