首页|Long-chain fatty acid acylated derivatives of isoflavone glycosides from the rhizomes of Iris domestica

Long-chain fatty acid acylated derivatives of isoflavone glycosides from the rhizomes of Iris domestica

扫码查看
Six undescribed long-chain fatty acid esters of isoflavone glycosides were obtained from the rhizomes of Iris domestica (L.). Their structures were elucidated by comprehensive spectroscopic data, alkaline hydrolysis, and acid hydrolysis. This is the first report of the long-chain (C14-C18) fatty acid derivatives of isoflavone glycosides from natural products. Belamcandnoate B and D exhibited moderate cytotoxic activities against HCT-116, HepG2, and BGC823 cell lines with IC50 values of 1.69-6.86 mu M. Belamcandnoate B and E exhibited 72.27 and 58.98% inhibitory activities, respectively, against Fe2+/cysteine-induced liver microsomal lipid peroxidation at a concentration of 10 mu M.

Iris domesticaIridaceaeLong-chain fatty acid derivativesCytotoxicityAntioxidationBELAMCANDA-CHINENSISMAGNETIC-RESONANCEQUERCETIN-3-O-GLUCOSIDEPHYTOCHEMISTRYESTERS

Liu, Yanfei、Wang, Renzhong、Yu, Dequan、Li, Jiayuan、Ni, Gang

展开 >

Chinese Acad Med Sci

2022

Phytochemistry

Phytochemistry

CCR
ISSN:0031-9422
年,卷(期):2022.193
  • 5
  • 29