首页|Development and characterization of the carvone-loaded zein/pullulan hybrid electrospun nanofibers for food and medical applications
Development and characterization of the carvone-loaded zein/pullulan hybrid electrospun nanofibers for food and medical applications
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NSTL
Elsevier
In this study, the carvone-loaded zein/pullulan electrospun nanofibers (Z/PUL/CAR NFs) were developed and characterized for the first time. The zein/pullulan hybrid NFs were produced at three different blending ratios of 90:10, 80:20, and 70:30 by electrospinning method. The zein/pullulan NFs at a ratio of 80:20 exhibited more homogeneous and bead-free, as well as the lowest average fiber diameter (508 +/- 159 nm). In this regard, this NFs was selected as the optimized sample for the incorporation of carvone. The Z/PUL/CAR NFs showed a bead free and cross-linked structure with an average fiber diameter of 588 +/- 288 nm. The compatibility among zein, pullulan, and carvone was approved by thermal gravimetric and X-ray diffraction analysis. Additionally, the Fourier transforms infrared spectroscopy indicated the formation of interactions among zein, pullulan, and carvone. The tensile strength and water contact angle values of Z/PUL/CAR NFs were 7.09 +/-& nbsp;0.85 MPa and 96.6 +/- 0.7, respectively. Moreover, the incorporation of carvone in the NFs provided DPPH scavenging activity (39.95 +/-& nbsp;3.81%) and inhibition activity against S. aureus (12.2 +/- 1.4 mm) and E. coli (9.6 +/- 1.2 mm) bacteria. The biocompatibility of developed NPs was approved by in-vitro cell cytotoxicity assay. In conclusion, the developed electrospun NFs have considerable potential for multiple applications such as food packaging and wound dressing.
NSTL
Elsevier
