首页|In vitro evidence suggesting that the toll-like receptor 7 and 8 agonist resiquimod (R-848) unlikely affects drug levels of co-administered compounds

In vitro evidence suggesting that the toll-like receptor 7 and 8 agonist resiquimod (R-848) unlikely affects drug levels of co-administered compounds

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Resiquimod (R-848) is an immune response modifier activating toll-like receptor 7 and 8. Its potential to cause pharmacokinetic interactions with concurrently administered drugs is unknown.

ResiquimodNuclear factor kappa BPregnane x receptorPharmacokinetic interactionsDrug transporter

Theile, Dirk、Wagner, Lelia、Haefeli, Walter E.、Weiss, Johanna

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Heidelberg Univ Hosp, Dept Clin Pharmacol & Pharmacoepidemiol, Im Neuenheimer Feld 410, D-69120

2021

European journal of pharmaceutical sciences

European journal of pharmaceutical sciences

ISTP
ISSN:0928-0987
年,卷(期):2021.162
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