首页|New iboga-type alkaloids from Ervatamia officinalis and their anti-inflammatory activity

New iboga-type alkaloids from Ervatamia officinalis and their anti-inflammatory activity

扫码查看
原文链接
  • NSTL
  • Elsevier
? 2021 Elsevier B.V.Four new iboga-type alkaloids, ervaoffines H-K (1–4), along with five known compounds were obtained from the aerial parts of Ervatamia officinalis. The absolute configurations of 1–4 were confirmed by X-ray diffraction and electronic circular dichroism (ECD) analyses. The isolates were tested for their anti-inflammatory activity. Compounds 1, 5, 6, and 9 showed potential inhibitory effect of NO production in LPS-stimulated BV2 and RAW264.7 cells.

Anti-inflammatoryErvaoffinesErvatamia officinalisIboga-type alkaloidsNO release

Tang B.-Q.、Yu G.-D.、Li Z.-W.、Chang Y.、Zhang X.-Q.、Li L.、Bian Y.-Q.、Lee S.M.-Y.、Li B.-J.

展开 >

Department of Medical Science Shunde Polytechnic

NMPA Key Laboratory for Quality Evaluation of TCM Jinan University

State Key Laboratory of Quality Research in Chinese Medicine Institute of Chinese Medical Sciences University of Macau

College of Traditional Chinese Medicine Yunnan University of Chinese Medicine

展开 >

2022

10.1016/j.fitote.2021.105085

Fitoterapia

Fitoterapia

SCI
ISSN：0367-326X
年,卷(期)：2022.156
  • 3
  • 17