A ring expansion approach to N-oxy-2,5-diketopiperazines
Jackson, Amy C. 1Olsen, James T. 1Sundstrom, Sasha 1Lambert, Kyle M. 1Wood, John L.1
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作者信息
1. Baylor Univ
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Abstract
A ring expansion of tetramic acids (pyrrolidine-2,4-diones) to N-oxy-2,5-diketopiperazines (DKPs) is described. This method allows for the facile and late-stage construction of the hydroxamic acid moiety and can thereby serve as a general method for accessing N-oxy-2,5-DKP natural products. (C) 2022 Elsevier Ltd. All rights reserved.
NSTL
Elsevier