首页|Phytochemical profile of Centevita?, a Centella asiatica leaves extract, and isolation of a new oleanane-type saponin
Phytochemical profile of Centevita?, a Centella asiatica leaves extract, and isolation of a new oleanane-type saponin
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NSTL
Elsevier
? 2022 Elsevier B.V.Centella asiatica is a popular medicinal plant and several phytotherapic products in the market include its extracts as active constituents. A LC-MS guided phytochemical investigation on the commercial C. asiatica leaves extract named Centevita? allowed characterization and quantification of 24 secondary metabolites including 10 polyphenols and 14 ursane- or oleanane-type triterpenoids in the sapogenin or saponin form. This metabolomic analysis, besides confirming that the triterpenoid fraction roughly accounts for 45% of the extract weight, also resulted in the discovery of isoterminoloside, a new triglycoside saponin of the unprecedented 2α,3β,6β,23-tetrahydroxyolean-13(18)-en-28-oic acid (isoterminolic acid). The structure of isoterminoloside was characterized by a detailed ESI-MS and NMR investigation.
NSTL
Elsevier
