A concise synthesis of indolo[2,1-a]isoquinoline via alkyne annulations promoted by base
Mehmood, Hina 1Iqbal, Muhammad Asif 1Hua, Ruimao1
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作者信息
1. Tsinghua Univ
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Abstract
A convenient and one-pot synthetic method for the construction of indolo[2,1-a]isoquinolines is developed by the dehydrative cyclocondensation reactions of the easily available 2-hydroxymethyl anilines with 2-ethynylbenzaldehydes in DMSO in the presence of KOH and TBAI under air. (C) 2021 Elsevier Ltd. All rights reserved.
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Elsevier