首页|Age stratified sex‐related differences in incidence, management, and?outcomes of cardiogenic shock

Age stratified sex‐related differences in incidence, management, and?outcomes of cardiogenic shock

扫码查看
原文链接
  • NSTL
  • Wiley
Abstract Background There is a lack of data on age‐stratified sex differences in the incidence, treatment, and outcomes of cardiogenic shock (CS). We sought to study these differences from a contemporary database. Methods Patients admitted with CS (2004–2018) were identified from the United States National Inpatient Sample. We compared CS (acute myocardial infarction‐related cardiogenic shock [AMI‐CS] and non‐acute myocardial infarction‐related cardiogenic shock [Non‐AMI‐CS]) incidence, management, and outcomes in males and females, stratified into four age groups (20–44, 45–64, 65–84, and ≥85 years of age). Propensity score matching (PSM) was used for adjustment. Results A total of 1,506,281 weighted hospitalizations for CS were included (AMI‐CS, 39%; Non‐AMI‐CS, 61%). Across all age groups, females had a lower incidence of CS compared with males. After PSM and among the AMI‐CS cohort, higher mortality among females compared with males was observed in the age groups 45–64?(28.5% vs. 26.3%) and 65–84 years?(39.3% vs. 37.9%) (p?<?0.01, for all). Among the Non‐AMI‐CS cohort, higher mortality among females compared with males was observed in the age groups?20–44 (33.5% vs. 30.5%), 45–64?(35.1% vs. 31.9%), and 65–84 years?(41.7% vs. 40.3%) (p?<?0.01, for all). Similar age‐dependent differences in the management of CS were also observed between females and males. Conclusions Females have a lower incidence of CS regardless of age. Significant disparities in the management and outcomes of CS were observed based on sex. However, these disparities varied by age and etiology of CS (AMI‐CS vs. Non‐AMI‐CS) with pronounced disparity among females in the age range of 45–84 years.

agecardiogenic shockdisparitygenderNational Trendssex

Mamas A. Mamas、Jinnette Dawn Abbott、Mohammed Osman、Moinuddin Syed、Babikir Kheiri、Christopher Bianco、Ankur Kalra、Joaquin E. Cigarroa、Sudarshan Balla、Gregg C. Fonarow、Cindy L. Grines

展开 >

Keele Cardiovascular Research Group,Keele University

Division of Cardiology,Warren Alpert Medical School of Brown University

Division of Cardiology,West Virginia University School of Medicine

Division of Cardiology, Knight Cardiovascular Institute,Oregon Health and Science University

Division of Cardiovascular Medicine, Krannert Cardiovascular Research Center,Indiana University

Division of Cardiology,David Geffen School of Medicine at University of California Los Angeles

Division of Cardiology,Northside Hospital Cardiovascular Institute

展开 >

2022

10.1002/ccd.30177

Catheterization and cardiovascular interventions

Catheterization and cardiovascular interventions

SCI
ISSN：1522-1946
年,卷(期)：2022.99(7)
  • 3
  • 39