首页|Two new isoquinoline alkaloids from Cryptocarya wrayi and their biological activities

Two new isoquinoline alkaloids from Cryptocarya wrayi and their biological activities

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? 2021Two new isoquinoline alkaloids, cryptowrayines A (1) and B (2), along with one known pavine alkaloid (-)-12-hydroxyeschscholtzidine (3), were isolated from the twigs of Cryptocarya wrayi. The structures of new compounds were elucidated by extensive spectroscopic data analysis and electronic circular dichroism (ECD) calculations. Both compounds 1 and 2 exhibited moderate quinone reductase inducing activity in Hepa 1c1c7 cells.

AlkaloidsCryptocarya wrayiECD calculationIsoquinoline

Liu Y.-L.、Wang Y.、Xu Y.-J.、Zhou Z.-W.、He X.-R.、Gan L.-S.、Xu F.、Wang X.-N.、Shen T.

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School of Pharmacy Nanchang University

Key Laboratory of Modern Preparation of TCM Ministry of Education Jiangxi University of TCM

School of Biotechnology and Health Sciences Wuyi University

College of Pharmaceutical Sciences Zhejiang University

Department of Natural Product Chemistry Key Laboratory of Chemical Biology (Ministry of Education) School of Pharmaceutical Sciences Shandong University

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2022

Fitoterapia

Fitoterapia

SCI
ISSN:0367-326X
年,卷(期):2022.156
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