Fitoterapia2022，Vol.1565.DOI:10.1016/j.fitote.2021.105086

Two new isoquinoline alkaloids from Cryptocarya wrayi and their biological activities

Liu Y.-L. Wang Y. Xu Y.-J. Zhou Z.-W. He X.-R. Gan L.-S. Xu F. Wang X.-N. Shen T.
Fitoterapia2022，Vol.1565.DOI:10.1016/j.fitote.2021.105086
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  • NSTL
  • Elsevier

Two new isoquinoline alkaloids from Cryptocarya wrayi and their biological activities

Liu Y.-L. 1Wang Y. 1Xu Y.-J. 1Zhou Z.-W. 1He X.-R. 2Gan L.-S. 3Xu F. 4Wang X.-N. 5Shen T.5
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作者信息

  • 1. School of Pharmacy Nanchang University
  • 2. Key Laboratory of Modern Preparation of TCM Ministry of Education Jiangxi University of TCM
  • 3. School of Biotechnology and Health Sciences Wuyi University
  • 4. College of Pharmaceutical Sciences Zhejiang University
  • 5. Department of Natural Product Chemistry Key Laboratory of Chemical Biology (Ministry of Education) School of Pharmaceutical Sciences Shandong University
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Abstract

© 2021Two new isoquinoline alkaloids, cryptowrayines A (1) and B (2), along with one known pavine alkaloid (-)-12-hydroxyeschscholtzidine (3), were isolated from the twigs of Cryptocarya wrayi. The structures of new compounds were elucidated by extensive spectroscopic data analysis and electronic circular dichroism (ECD) calculations. Both compounds 1 and 2 exhibited moderate quinone reductase inducing activity in Hepa 1c1c7 cells.

Key words

Alkaloids/Cryptocarya wrayi/ECD calculation/Isoquinoline

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出版年

2022
Fitoterapia

Fitoterapia

SCI
ISSN：0367-326X
被引量3
参考文献量24
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