首页|Cryoanalgesia is Associated With Decreased Postoperative Opioid Use in Minimally Invasive Repair of Pectus Excavatum

Cryoanalgesia is Associated With Decreased Postoperative Opioid Use in Minimally Invasive Repair of Pectus Excavatum

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Background: Postoperative pain control is challenging after pectus excavatum repair. We aimed to understand the impact that cryoanalgesia had on opioid utilization and outcomes of pediatric patients undergoing minimally invasive repair of pectus excavatum (MIRPE). Methods: A single-center retrospective cohort study was conducted of all patients (< 18 y) who underwent MIRPE (2011-2019). Patients receiving cryoanalgesia were compared to those who did not. The primary outcome was total postoperative, inpatient, opioid use, measured as milligrams of oral morphine equivalents per kilogram (OME/kg). Univariate and multi variable analyses were performed. Results: Of 35 patients, 20 received cryoanalgesia (57%). Baseline characteristics were similar. Patients who received cryoanalgesia had a lower opioid requirement: median 2.3 mg OME/kg (IQR 1.2-3.1), versus 4.9 mg OME/kg (IQR 2.9-5.8), P < 0.001. Accounting for receipt of cryoanalgesia, epidural, and/or patient-controlled analgesia, cryoanalgesia was associated with a 3.3 mg OME/kg reduction in opioid use ( P < 0.001). Median length of stay (LOS) was shorter in cryoanalgesia patients: 3.1 d (IQR 2.3-3.4), versus 5.1 d (IQR 4.3-5.4), P < 0.001. Complications within 90 d were similar between groups.

Pectus excavatumCryoanalgesiaPain controlLength of StayNuss procedureMinimally Invasive Repair of PectusExcavatumINTERCOSTAL NERVE CRYOABLATIONNUSSOUTCOMESPAIN

Arshad, Seyed A.、Ferguson, Dalya M.、Garcia, Elisa, I、Hebballi, Nutan B.、Buchanan, Allison C.、Tsao, KuoJen

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McGovern Med Sch,Univ Texas Hlth Sci Ctr Houston

Dept Anesthesiol,Univ Texas Hlth Sci Ctr Houston

2022

The Journal of surgical research.

The Journal of surgical research.

ISSN:0022-4804
年,卷(期):2022.271
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