首页|Extracts and fractions of Croton L. (Euphorbiaceae) species with antimicrobial activity and antioxidant potential

Extracts and fractions of Croton L. (Euphorbiaceae) species with antimicrobial activity and antioxidant potential

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  • NSTL
  • Elsevier
The growing microbial resistance to antibiotics and the adverse effects of the frequent use of antimicrobials in oral medicine require products as natural therapeutic alternatives. Croton betaceus and C. lundianus can be viable for in-depth studies in search of new biopmducts. This study evaluated the antioxidant and antimicrobial potential of ethanol extract and leaf fractions of Croton spp. The disk diffusion assay, FRAP and DPPH, were used for antimicrobial and antioxidant analysis, respectively. In addition to phytochemical prospecting and toxicity testing. Secondary metabolites with biological activities were found. Researched extracts and fractions have the potential to inhibit the growth of oral pathogens (Gram-positive, Gram-negative and yeast) in different concentrations. Enterococcus faecalis is the most susceptible to the extract. All fractions showed antioxidant potential. The hexane fraction (BHX and LHX) of both species can inhibit the growth of pathogens in low concentrations, and has a high antioxidant power. The fractions of the extracts of C. betaceus and C. lundianus have important biological activities that can be applied in the development of new antimicrobials for industry and other biotechnological applications.

Antimicrobial activityAntioxidant activityCroton betaceusCroton lundianusFolk medicineHexane fraction

Rocha, Andre R. F. da S.、Sousa, Herbert G.、do Vale Junior, Erasmo P.、de Lima, Francisca L.、Costa, Anabela S. G.、de Araujo, Alyne R.、Leite, Jose Roberto S. A.、Martins, Francielle A.、Oliveira, M. Beatriz P. P.、Placido, Alexandra、Filho, Francisco S. S.、Lago, Eliana C.

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Univ Estadual Maranhao, Dept Hlth Sci, UEMA, BR-65604380 Caxias, Maranhao, Brazil

Univ Estadual Piaui, Ctr Nat Sci, UESPI, BR-64002150 Teresina, PI, Brazil

Univ Porto, Fac Pharm, Dept Chem Sci, FFUP,LAQV REQUIMTE, P-4050313 Porto, Portugal

Fed Univ Delta Parnaiba, Biotechnol & Biodivers Ctr Res, Biotec, UFDPar, BR-64202020 Parnaiba, PI, Brazil

Univ Brasilia, Ctr Res Appl Morphol & Immunol, NuPMIA, UnB, BR-70910900 Brasilia, DF, Brazil

Univ Porto, Fac Sci, Dept Chem & Biochem, FCUP,LAQV REQUIMTE, P-4169007 Porto, Portugal

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2021

10.1016/j.lwt.2020.110521

LWT-Food Science & Technology

LWT-Food Science & Technology

ISSN：0023-6438
年,卷(期)：2021.139
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