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COVID-19 associated nervous system manifestations

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The novel coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome corona-virus 2 (SARS-CoV-2), has caused a global pandemic in the last year. Along with major respiratory distress, a myriad of neurological manifestations was also reported to be associated with COVID-19 patients. These cases indicate that SARS-CoV-2 can be considered as an opportunistic pathogen of the brain. SARS-CoV-2 enters the brain through the olfactory bulb, retrograde axonal transport from pe-ripheral nerve endings, or via hematogenous or lymphatic routes. Notably, COVID-19 infection can cause or even present with different neurological features including encephalopathy, impaired consciousness, confusion, agitation, seizure, ataxia, headache, anosmia, ageusia, neuropathies, and neurodegenerative diseases. In this paper, we provide a brief review of observed neurological manifestations associated with COVID-19.(c) 2021 Elsevier B.V. All rights reserved.

COVID-19SARS-CoV-2Neurological manifestationsNeurodegenerative diseasesNeuroinvasionSleepRESPIRATORY SYNDROME CORONAVIRUSVIRUSINFECTIONDISEASEBRAIN

Prasad, Kartikay、Kumar, Vijay、Khatoon, Fatima

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Am Inst Neuropsychol & Neurosci,Am Univ

2022

Sleep medicine

Sleep medicine

SCI
ISSN:1389-9457
年,卷(期):2022.91
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