首页|Determinants of rapid infant weight gain: A pooled analysis of seven cohorts

Determinants of rapid infant weight gain: A pooled analysis of seven cohorts

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Summary Objective Rapid weight gain (RWG) in infancy is strongly associated with subsequent obesity risk, but little is known about the factors driving RWG. This study explored the child and maternal factors associated with infant RWG. Methods Data from seven Australian and New Zealand cohorts were used (n?=?4542). Infant RWG was defined as a change in weight z‐score?≥0.67 from birth to age 1 year. Univariable and multivariable logistic regression assessed the association between child and maternal factors and infant RWG in each cohort. Meta‐analysis was conducted to obtain pooled effect sizes. Results Multivariable analyses revealed boys were more likely to experience RWG (OR 1.42 95% CI 1.22, 1.66) than girls. Higher birth weight in kg (OR 0.09, 95% CI 0.04, 0.20) and gestational age in weeks (OR 0.69, 95% CI 0.48, 0.98) were associated with lower RWG risk. Children who were breastfed for ≥6?months showed lower RWG risk (OR 0.45, 95% CI 0.38, 0.53). Children of native‐born versus overseas‐born women appeared to have higher RWG risk (OR 1.37, 95% CI 0.99, 1.90). Maternal smoking during pregnancy increased RWG risk (OR 1.60, 95% CI 1.28, 2.01), whereas children who started solids ≥6?months (OR 0.77, 95% CI 0.63, 0.93) and children with siblings (OR 0.68, 95% CI 0.57, 0.81) showed lower RWG risk in univariable analysis, but these associations were attenuated in multivariable analysis. No association was found for maternal age, education, marital status and pre‐pregnancy BMI. Conclusion Maternal country of birth, smoking status, child sex, birth weight, gestational age, infant feeding and parity were potential determinants of infant RWG.

birth weightdeterminantsinfantinfant feedingpooled analysisrapid weight gain

Miaobing Zheng、Kylie D. Hesketh、Peter Vuillermin、Jodie Dodd、Li Ming Wen、Louise A. Baur、Rachael Taylor、Rebecca Byrne、Seema Mihrshahi、Peter D. Sly、Mimi L. K. Tang、Karen J. Campbell

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Deakin University, Institute for Physical Activity and Nutrition, School of Exercise and Nutrition

Barwon Health

Discipline of Obstetrics and Gynaecology,The Robinson Research Institute, The University of Adelaide

School of Public Health and Sydney Medical School,The University of Sydney

Department of Medicine,University of Otago

School of Exercise and Nutrition Sciences, Faculty of Health,Queensland University of Technology

Department of Health Sciences, Faculty of Medicine,Health and Human Sciences, Macquarie University

Children's Health and Environment Program,The University of Queensland

Murdoch Children's Research Institute

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2022

10.1111/ijpo.12928

Pediatric obesity.

Pediatric obesity.

ISSN：2047-6302
年,卷(期)：2022.17(10)
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