首页|Preparation of antibacterial chlorhexidine/vermiculite and release study
Preparation of antibacterial chlorhexidine/vermiculite and release study
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NSTL
Elsevier
The antibacterial chlorhexidine/vermiculite (CA/Ver) was successfully prepared through the intercalation process and the stability of CA on the vermiculite matrix and was investigated by stirring in aqueous solutions under the influence of different pH and temperature. The content of CA was determined by total organic carbon (TOC) analysis before and after stability tests. The structure of all samples was characterized by X-ray powder diffraction (XRD) and Fourier-transform infrared spectroscopy (FTIR). The antibacterial activity of prepared CA/Ver samples was evaluated by finding a minimum inhibitory concentration (MIC) against Entero coccus faecalis, Staphylococcus aureus, Escherichia coil and Psetidomonas aeruginosa. The content of chlorhexidine ranged from 209 to 231.6 mg of CA in 1 g of the whole sample after the intercalation process. After stability study, only a slight outflow of CA from the Ver matrix (<5%) was noted. The antibacterial test confirmed that the outflow of CA was negligible.
VermiculiteChlorhexidine diacetateAntibacterial activityStability test
Samlikova, Magda、Holesova, Sylva、Hundakova, Marianna、Pazdziora, Erich、Jankovic, Lubos、Valaskova, Marta
NSTL
Elsevier
