首页|Pipeline flex embolization device for the treatment of large unruptured posterior circulation aneurysms: Single-center experience

Pipeline flex embolization device for the treatment of large unruptured posterior circulation aneurysms: Single-center experience

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? 2021 Elsevier LtdPurpose: To investigate the safety and effect of the Pipeline Embolization Device (PED) Flex device in the treatment of large unruptured posterior circulation aneurysms in a single center. Materials and methods: Patients with large unruptured posterior circulation aneurysms which were treated with the PED Flex device were enrolled. The clinical, endovascular and follow-up data were analyzed, and the O'Kelly-Marotta (OKM) grading system was used to assess the aneurysm occlusion status. Results: Fourteen patients with 14 large posterior circulation aneurysms who were treated with the PED Flex device were enrolled. The maximal diameter of aneurysm was 17.0 ± 3.9 mm. Fourteen PED Flex devices were deployed in 14 patients, with a technical success rate of 100%. All stents covered the aneurysm neck with good wall adherence and patent parent artery. Ten (71.4%) aneurysms were treated with a single PED Flex device each, and four (28.6%) patients experienced additional coiling. No neurological complications occurred in the periprocedural period. The mRS was 0 in eleven (78.6%) patients, 1 in two (14.3%), and 2 in one (7.1%) at discharge. All patients were followed up at 6–28 months (median 18), with an mRS score of 0 in all patients. Twelve (85.7%) patients experienced digital subtraction angiography 6–28 (median 18) months after the embolization procedure, and the OKM grade was D in nine (75%), C in two (16.7%), and B in one (8.3%). Conclusion: The Pipeline Flex Embolization Device can be safely applied to treat large unruptured posterior circulation aneurysms with a high complete aneurysm occlusion rate at follow-up.

ComplicationsEffectLarge unruptured aneurysmsPipeline flex embolization devicePosterior circulation

Li L.、Gao B.-L.、Wu Q.-W.、Shao Q.-J.、Wang Z.-L.、Zhang K.、Li T.-X.

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Henan Provincial People's Hospital Zhengzhou University

2022

Journal of clinical neuroscience

Journal of clinical neuroscience

SCI
ISSN:0967-5868
年,卷(期):2022.96
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