首页|Two new lignans with their biological activities in Portulaca oleracea L.

Two new lignans with their biological activities in Portulaca oleracea L.

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  • NSTL
  • Elsevier
? 2022 Phytochemical Society of EuropeTwo new lignans, identified as 6,7-dihydroxy-4-(4′’-hydroxy-3′’-methoxyphenyl)-2-naphthoic acid, named Oleralignan C (1), and 4-(3,4-dihydroxyphenyl)-6-hydroxy-7-methoxy-2-naphthoic acid, named Oleralignan D (2), were obtained from Portulaca oleracea L. The structures were determined by spectroscopic methods, including UHPLC-ESI-QTOFMS, 1D and 2D NMR. Both Oleralignan C (1) and Oleralignan D (2) inhibited the inflammatory factors, IL-1β and TNF-α in RAW 264.7 cells induced by lipopolysaccharide (LPS). Both compounds also could clear 1,1-diphenyl-2-picryl-hydrazyl (DPPH) radicals indicating their antioxidant potential.

Anti-inflammatory activityAntioxidant activityLignanOleralignanPortulaca oleracea L.

Wang C.、Guo S.、Tian J.、Liu P.、Song M.、Zhang W.、Ying X.

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School of Pharmacy Liaoning University of Traditional Chinese Medicine

2022

10.1016/j.phytol.2022.06.003

Phytochemistry Letters

Phytochemistry Letters

SCI
ISSN：1874-3900
年,卷(期)：2022.50
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